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Access to Mifepristone Still in Legal Limbo
A federal judge may block the use of the safe and effective abortion drug mifepristone after hearing a lawsuit by an anti-abortion organization. The group claimed the FDA had improperly approved mifepristone in 2000.
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Controlling Blood Pressure During Pregnancy Could Lower Dementia Risk
Investigators found an association between high blood pressure during pregnancy and a higher likelihood of developing dementia later in life.
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Mediterranean Diet Pairs Well with Immune Checkpoint Blockade
The popular healthy diet boosted response to unique cancer therapy among patients with advanced melanoma.
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Vitamin D3, Omega-3, and Their Effects on Frailty in Older Patients
Data from a large, randomized trial that included 25,871 adults age 50 years or older indicated 2,000 daily units of vitamin D3 and 1 g daily of omega-3 fatty acid supplementation did not affect frailty.
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Multivitamin-Mineral Supplementation vs. Cocoa Extract for Cognition
This large, randomized trial followed participants for three years and determined that daily use of a cocoa supplement was not associated with cognitive enhancement in older adults, whereas a multivitamin supplement was associated with significant cognitive benefits.
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Infectious Disease Alert Updates
California Firefighters at Risk for Cocci; Hyperglycemia and Diabetes with INSTIs; Positive Sputum in Extra-Pulmonary Tuberculosis
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Comparison of Postoperative Antibiotic Regimens for Complex Appendicitis: Is Two Days as Good as Five Days?
In a pragmatic, open-label, randomized trial conducted at 15 hospitals in the Netherlands, two days of postoperative intravenous antibiotics for complex appendicitis was found to be noninferior to five days in terms of infectious complications and mortality within 90 days.
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Does COVID Vaccination Prevent Car Crashes?
In a large Canadian study, lack of COVID vaccination was associated with an increased incidence of being injured in a car crash.
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Fungal Meningitis After Epidural Injections — Again
An outbreak in Mexico of meningitis due to Fusarium solani has affected at least 79 patients who had received epidural injections; at least 35 have died.
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Nationwide Outbreak of Extensively Drug-Resistant Pseudomonas aeruginosa Infections from Contaminated Eye Drops
An outbreak of extensively drug-resistant Pseudomonas aeruginosa infection has been traced to use of contaminated artificial tears.