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Although current guidelines recommend delaying neuroprognostication during therapeutic hypothermia following resuscitation from cardiac arrest, this review of 55 consecutive patients so managed found that a "poor prognosis" designation was arrived at during the hypothermia period in most of them, including six patients who were eventually discharged with a favorable neurologic outlook.
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Wunsch and associates describe two patients who suffered respiratory arrest requiring intubation and mechanical ventilation while receiving polymyxin B.
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In this issue: Statins and diabetes risk; new treatment guideline for diabetes; new pertussis vaccine recommendation; antibiotics and rhinosinusitis; fluoroquinolones and cystitis; and FDA actions.
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Angiotensin-converting enzyme inhibitor (ACEI) therapy may be beneficial during coronary artery bypass graft (CABG) surgery because of its anti-inflammatory and other vascular benefits.
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Various risk schemes have been promulgated for assessing the risk of stroke and bleeding in patients with atrial fibrillation (AF). These investigators used the Swedish Atrial Fibrillation cohort study to investigate the comparative utility of four schemes that have been validated in AF cohorts: CHADS2, CHA2DS2-VASc, HAS-BLED, and HEMORR2HAGES.
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In this paper, the authors perform a systematic review and meta-analysis of published reports comparing anticoagulation management strategies around the time of cardiac rhythm device implantation. Using standard techniques, the authors searched the medical literature and identified studies that assessed two or more anticoagulation strategies around the time of cardiac rhythm device implantation.
