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Sustained release bupropion treatment is an efficacious aid to smoking cessation for patients at risk for and with chronic obstructive pulmonary disease.
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Esomeprazole 20 mg and 40 mg daily improve upper GI symptoms occurring during NSAID therapy including selective COX-2 inhibitors.
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Death rates in the year after bariatric surgery were high (4.6%), and were higher for men, for those older than 65, and for those whose surgeon performed fewer than 35 such operations a year.
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The use of an attenuated varicella zoster virus vaccine, many times more potent than that used in children for the prevention of chickenpox, was effective in the prevention of both herpes zoster and postherpetic neuralgia in individuals 60 years of age and older.
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The FDA has approved nelarabine for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and lymphoblastic leukemia (T-LBL). Nelarabine was approved under the FDAs accelerated approval program. It received an Orphan Designation because it is for a rare disease affecting less than 200,000 in the United States. Nelarabine is marketed by GlaxoSmithKline as Arranon®.
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Should Empiric Treatment be Given to women with UTI Sx but negative U/A?; Is Routine Fundoscopy Worth the Bother in Hypertension?; Autoantibody Signatures in Prostate Cancer
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Neuraminidase inhibitors are a class of antivirals that have activity against both influenza A and B viruses. Influenza neuraminidase cleaves terminal sialic acid residues and damages the receptors recognized by viral hemagglutinin, thereby facilitating release of virus from infected cells. In the presence of a neuraminidase inhibitor, release of virus from infected cells is impaired and the progeny viruses that are freed clump together, as sialic acid has not been cleaved.
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A meta-analysis of the medical literature shows that self-monitoring of blood glucose by type 2 diabetics not on insulin does not improve control of the disease compared with regular monitoring of hemoglobin A1c (HbA1c). Patients spend considerable time and resources with daily monitoring of their blood sugars. Physicians increasingly rely on quarterly HbA1c levels as a marker of control.
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