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Withdrawal of statin therapy in acute ischemic stroke may lead to increases in death and disability.
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Carcinoma of unknown primary remains a management problem without an established approach demonstrated to prolong survival. In a phase II study, the combination of carboplatin, gemcitabine, and capecitabine was shown to be fairly well tolerated and, for certain subsets, effective in producing transient tumor regression.
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When used in conjunction with clinical and radiographic data, brain natriuretic peptide levels may provide a non-invasive alternative for distinguishing between ARDS and cardiogenic pulmonary edema in patients with severe hypoxemic respiratory failure.
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Although ECG is the standard initial screening test for acute coronary syndromes, its value for the diagnosis of acute myocardial infarction (MI) is difficult to determine because of the vagaries of serum biomarkers.
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Exceptional attention has been paid to the recent publication of the COURAGE Trial (April 2007) regarding the efficacy of percutaneous coronary intervention (PCI) in stable coronary disease patients, whereas in acute coronary syndromes, including STEMI and unstable angina, there is reasonable consensus as to an interventional approach in patients with either PCI or CABG as opposed to medical therapy.
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Are thiazolidinediones safe? New study shows Zometa reduces risk of hip fractures and improves survival; Merck HIV vaccine proven ineffective in clinical trials; no causal association found between exposure to mercury from thimerosal; and FDA approvals.
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The effectiveness of off-pump coronary artery bypass graft surgery (OPCAB) is controversial. Thus, Hannan and colleagues from New York evaluated the short-term and long-term results of OPCAB with sternotomy vs on-pump CABG in New York State between 2001-2004.
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This paper reports the results of the Search AV Extension and Managed Ventricular Pacing for Promoting Atrioventricular Conduction (SAVE PACe) Trial. This study evaluated the use of pacing algorithms that were designed to minimize the percentage of ventricular pacing in patients with symptomatic sinus-node dysfunction.
