Cardiology
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Home-based Detection of Undiagnosed Atrial Fibrillation
In patients with risk factors for atrial fibrillation, screening with a self-applied wearable ECG patch resulted in significantly increased rates of new atrial fibrillation diagnoses within four months, along with greater use of anticoagulants and healthcare resources.
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Canagliflozin Reduces Risk of Heart Failure Hospitalizations for Diabetic Patients
In type 2 diabetes mellitus patients with a higher risk of cardiovascular disease, canagliflozin lowered the risk of cardiovascular death or heart failure hospitalization. Patients with pre-existing heart failure may experience even greater benefit.
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Negative Fluid Balance on Day 3 Associated With Improved Outcomes in Critical Illness
In critically ill patients, a negative fluid balance on day 3 either spontaneously or with deresuscitative measures may be associated with lower mortality.
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ECMO vs. Optimal Protective Ventilation and Ancillary Therapies in Severe ARDS
Treatment of very severe acute respiratory distress syndrome with venovenous extracorporeal membrane oxygenation vs. lung-protective ventilation with aggressive ancillary therapy use demonstrated only a trend toward improved 60-day mortality.
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The Opioid Crisis in the ICU
A detailed exploration of the background of the opioid crisis and how it affects the ICU.
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Cannabidiol Oral Solution (Epidiolex)
Epidiolex is indicated for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome in patients ≥ 2 years of age.
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A Negative Nares Screen for MRSA Helps Exclude MRSA Pneumonia
The authors of a meta-analysis determined that nares screening for methicillin-resistant Staphylococcus aureus (MRSA) has a high specificity and negative predictive value for MRSA pneumonia.
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Vitamin D and Glycemic Control in Patients With Type 2 Diabetes
Findings from a meta-analysis show vitamin D supplementation was associated with improved glycemic control in vitamin D-deficient or non-obese patients with type 2 diabetes.
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Tailored Anticoagulation for Paroxysmal Atrial Fibrillation
Intermittent anticoagulation guided by continuous assessment of arrhythmia status in patients with low-to-moderate risk did not result in any strokes or thromboembolic events over a relatively short follow-up period.
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Timing of Protein Intake Does Not Influence Muscle Mass or Strength
The timing of protein intake during or between meals does not play a role in anabolic response, muscle strength, or functional outcomes.