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In patients with stable coronary artery disease and atrial fibrillation (AF) on oral anticoagulants, adding antiplatelet agents is common and recommended in guidelines, especially during the first year after an acute coronary event or revascularization.
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The mortality benefit to percutaneous coronary intervention (PCI) is unquestioned when it comes to ST-elevation myocardial infarction (STEMI).
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In patients with severe degenerative mitral regurgitation (MR), surgery is clearly recommended in the presence of any symptoms.
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Hydrocodone is formulated to resist crushing, breaking, and dissolution and still retain some extended-release properties.
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Because of its strong efficacy, long-term durability, and predictability when titrated with algorithms employed in clinical trials, basal insulin remains a mainstay of treatment for type 2 diabetes patients who are not able to attain or maintain glycemic control with oral agents alone. Because diabetes is a progressive disorder, even patients who are initially well-controlled on basal insulin will likely require “fine tuning” of their diabetes regimen, usually with agents that preferentially affect postprandial glucose levels.
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Although not a life-threatening condition, benign prostatic hypertrophy (BPH) is one of the most annoying and troublesome problems that plagues aging males.
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Due to the short half-life and rapid onset of action of the new oral anticoagulants (NOACs), peri-procedural anticoagulant free time intervals should be shorter than with warfarin. Thus, there is uncertainty about the use of heparin bridging.
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Bioprosthetic aorta valves are recommended for those > 70 years of age because of their reduced durability compared to mechanical valves and mechanical prostheses, which are recommended for those < 60 years because bioprosthetic valves deteriorate more rapidly in younger individuals.
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