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The Defibrillator in Acute Myocardial Infarction Trial examined the question whether prophylactic implantable cardioverter defibrillator (ICD) therapy begun soon after myocardial infarction would reduce long-term mortality.
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The addition of antiplatelet therapy to reduced intensity anticoagulation in atrial fibrillation patients reduces death and embolic events without increasing bleeding.
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The substantial differences in opinion concerning the need for revascularization prior to elective vascular surgery are present among cardiologists.
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Pravastatin is the statin with the least interactions with cytochrome P450-(CYP) 3A4 inhibitors.
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Atenolol is unsuitable as a first-line drug in hypertension.
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Pharmacotherapy of hypertension has been much in the news in the last 2 months. Standard therapies such as atenolol have been challenged, while calcium channel antagonists may be making a comeback.
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The addition of nifedipine to conventional treatment in patients with chronic stable angina did not affect overall event-free survival, but was safe and reduced the need for coronary interventions.
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Tailored doses of anesthesia can improve the safety and quality of patient care dramatically during and immediately after surgery, and may even reduce postoperative mortality rates in the longer term, report physicians from the Medical College of Georgia and MCG Health System in Augusta.
