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Raloxifene treatment of postmenopausal women with osteoporosis is associated with a lower incidence of estrogen receptor-positive invasive breast cancer.
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Over the last few decades, technology has existed to evaluate the cytotoxic effects of single-agent and combination chemotherapy on cancer cell lines derived from an individual patient's tumor specimens. However, investigators and clinicians have been frustrated as the fruit of this technologya reliable and reproducible assay to help them treat their patients with the agent or agents most likely to benefit themhas yet to be proven.
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GEMINI Trial, CAMELOT Trial, INVEST Trial, The Dangers of Vitamin E, FDA Actions.
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Despite its relative brevity, the Belmont Report has withstood the test of time as a framework for ethical decision making about human subjects research, experts in research ethics say.
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Clinical Trials Administrator asked Bernard Schwetz, DVM, PHD, director of the Office of Human Research Protections (OHRP) to discuss the Belmont Reports successes and challenges as the 25th anniversary of its launching has passed. Schwetz offers his views in this Q&A.
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Clinical trials administrators and other research staff could avoid common problems after research has been completed if they would follow a well-defined, closeout process, regardless of the type of award that was made, according to a research expert.
