– December 1, 2006
December 1, 2006
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Imatinib Improves Outcomes in Elderly Patients with Ph+ ALL
Acute lymphocytic leukemia (ALL) in the elderly is not common, but as in younger adults, a subset will be Philadelphia chromosome postitive (Ph+). In young patients with Ph+ ALL, the addition of imatinib has been shown to be effective in enhancing complete response rates and relapse-free survival. -
Outpatient Azacitidine for Selected AML Patients
A review of twenty AML patients who were treated with azacitidine demonstrated a response rate of 60% and for those that responded, a median survival of 15+ months. -
AMG 531 Promotes Thrombopoiesis in ITP
ITP is usually a chronic condition in adults resulting from both platelet destruction and impaired production. This study summarizes the early phase experience in two trials for chronic refractory ITP of AMG 531, a novel thrombopoiesis stimulating protein. -
Adjuvant Chemotherapy (Yes or No) After Colorectal Liver Metastases Resection
The question of the role for systemic therapy in addition to surgical resection of liver metastases was addressed by Portier and colleagues from France. -
Therapeutic Role of Lymph Node Resection in Endometrioid Corpus Cancer
The findings of the current study suggest that the extent of lymph node resection improves the survival of women with intermediate/high-risk endometrioid uterine cancer. -
Pharmacology Watch
In response to several high-profile drug misadventures including the rofecoxib (Vioxx®) withdrawal from the market, the FDA's Center for Drug Evaluation and Research (CDER) asked the Institute of Medicine (IOM) to assess the drug safety system in the United States. -
Clinical Briefs in Primary Care Supplement