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Pediatric Airway Management: Difficult Airways
One of the most critical aspects of pediatric emergency medicine is handling a critical airway in a child. The authors provide comprehensive guidance on preparation, recognition and management to achieve success in this challenging situation.
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Post-Traumatic Headaches: Common and Complicated
The brain’s ability to modulate pain influences the development and persistence of post-traumatic headache (PTH). Functional magnetic resonance imaging (fMRI) studies in people with PTH show higher pain-induced brain activation in specific regions, such as the postcentral gyrus, superior temporal gyrus, and ventral striatum, as compared to healthy controls. Over 16 weeks of observation, progressive normalization in pain-induced brain activation was seen in the PTH group with headache improvement, with persistently elevated activation in the non-improvement PTH group.
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Epilepsy in Frontotemporal Dementia
This Finnish case-control study explores the relationship between frontotemporal dementia (FTD) and epilepsy, revealing that individuals with FTD have a higher prevalence of epilepsy compared to those with Alzheimer’s disease (AD) and healthy controls. The findings suggest that epilepsy may precede FTD diagnosis and is more common in FTD than previously recognized, highlighting the need for broader research and clinical awareness of this comorbidity.
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Use of IV Tenecteplase Prior to Thrombectomy in Stroke
In patients with acute ischemic stroke arriving at a thrombectomy-ready hospital within 4.5 hours of stroke onset, the combination of treatment with intravenous tenecteplase followed by mechanical thrombectomy resulted in superior outcomes compared to thrombectomy alone.
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Rituximab to Prevent Relapse in Anti-NMDAR Antibody-Mediated Encephalitis
This long-term follow-up study of 67 patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis demonstrated that initial treatment with rituximab was associated with a longer time before a relapse occurred.
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Treating Small Vessel PCNSV with Cyclophosphamide
In this single-center study, 26 adults with biopsy-confirmed small vessel primary central nervous system vasculitis (PCNSV) were followed for a median of 49 months. Patients receiving early treatment with cyclophosphamide within three months of immunosuppression initiation achieved remission faster than those receiving conservative initial treatment with corticosteroids, either as monotherapy or with azathioprine, mycophenolate, or methotrexate. Retrospective design, treatment selection bias, small sample size, and clinicopathologic heterogeneity limit therapeutic inferences and highlight the need for prospective trials.
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Georgia Supreme Court Revives Vicarious Liability Claim
The Georgia Supreme Court has revived a vicarious liability claim in a medical malpractice lawsuit that raises important questions about the role of medical students and the legal responsibility of supervising physicians. The case stems from a surgical injury that occurred during a 2019 hysterectomy, in which a medical student under the supervision of two attending physicians allegedly caused harm by misplacing a surgical instrument.
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Trial Court’s ‘Confusing’ Instruction Did Not Doom Verdict, Appeals Court Says
A Georgia appellate court has reinstated a defense verdict in a closely watched medical malpractice case arising from complications following a total knee replacement. The case centered on a plaintiff who alleged that a surgeon failed to promptly diagnose and treat a postoperative infection in his left knee.
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Alternative Dispute Resolution Underused in Most Hospitals
Hospitals have been slow to make use of alternative dispute resolution (ADR) agreements to avoid litigation and bring about more satisfactory conclusions to claims.
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Executive Protection May Need Review After CEO Killing
The shooting of Brian Thompson in December 2024 has brought attention to the security needs of healthcare executives, with some in the industry suggesting that organizations should devote resources to increased protection.