Articles Tagged With:
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Ibrexafungerp for Vulvovaginal Candidiasis
A randomized clinical trial compared one day of oral ibrexafungerp with placebo for female patients with vulvovaginal candidiasis (VVC). It found ibrexafungerp to be safe and effective, with mild diarrhea the most common adverse event. Ibrexafungerp differs mechanistically from azoles and appears to be a promising new treatment for VVC.
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Effectiveness of an Online e-Health Program in Ameliorating Postpartum Depression
This study demonstrated that combined use of universal depression screening and MomMoodBooster2, a cognitive behavioral therapy-based e-health program, were effective tools for treating women with depression in the perinatal period.
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A Simple Intervention to Reduce Surgical Site Infections?
This multicenter, cluster randomized trial in Benin, Ghana, India, Mexico, Nigeria, Rwanda, and South Africa evaluated the effect of changing sterile gloves and instruments at the time of abdominal wound closure on surgical site infection (SSI) rates among adults and children undergoing both elective and emergent surgery. The SSI rate in the intervention group among 5,789 patients was 16% compared to 18.9% in the control group of 6,768 patients (adjusted risk ratio, 0.87; 95% confidence interval, 0.79-0.95).
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Data Indicate Hospital Stays Are Longer, Causing Discharge Delays
As patients wait longer to take the next step along their journey through the healthcare continuum, costs mount for providers.
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Tissue Donors Can Track How Researchers Use Samples
Tissue donors never knew who used their samples or how. For the first time, tissue donors are using blockchain technology to track how scientists use their samples through a pilot program.
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Tricky Business: When a Surgeon Also Is a Researcher
Consider this seemingly innocent, straightforward question: “Would you be interested in participating in a clinical trial?” Now consider the ethical implications if a surgeon asks his or her own patient the same question.
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What Happens if Your Study Fails to Meet Recruitment Targets?
Failure to find enough clinical trial participants is more than just a logistical problem. There also are important ethical concerns. If the study remains incomplete, investigators risk violating the principle of beneficence.
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Clinicians Often Use Medical Jargon to Refer to Death
During family meetings, ethicists can gently clarify language to ensure everyone understands. Even the best communicators will encounter patients and families who will not or cannot hear the words spoken to them, especially if it is bad news.
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When Researchers Discover Incidental Findings During Clinical Trial
If a study includes genomic testing, it is possible incidental findings will be discovered. As it stands, there is no clear guidance for whether researchers should tell participants about those findings.
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Clinicians Are Ethically Obligated to Consider Financial Side of Care
Clinicians should include the cost of care in discussions, help patients access charity care or financial counseling, and screen patients for social determinants of health.