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The diagnosis and management of patients with manifestations of drug-induced cardiotoxicity is challenging for even the most experienced emergency physician. The following report reviews the pathophysiology and clinical manifestations of cardiotoxins to provide the front-line practitioners with evidence-based protocols for managing patients with life-threatening toxicity.
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Child abuse can be difficult to recognize, especially in the often chaotic environment of the emergency department. As the leaders of the community and medical safety net that is the ED, emergency physicians play a unique role in detecting, treating, and preventing child abuse. This issue of Emergency Medicine Specialty Reports provides an update on the patterns, diagnosis, and treatment of physical child abuse injuries.
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There are increasing numbers of women who have been cured of cancer but have residual endocrine and reproductive ovarian failure. In the current report, a novel approach for reconstituting ovarian function in selected patients is presented.
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Only tamoxifen has enough evidence to recommend it for the prevention of breast cancer, and its use is limited to very high-risk women with a low risk of side effects.
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The value of neoadjuvant chemotherapy for invasive bladder cancer had not been definitively established, possibly because clinical trials have been of insufficient size to demonstrate efficacy.
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In a multicenter trial from Japan, Bestatin, an aminopeptidase inhibitor, was shown to enhance survival in patients with stage I sqaumous cell carcinoma of the lung.
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There have been no randomized trials comparing surgery and radiotherapy for solitary brain metastases, nor are there well-defined guidelines for the management of these patients.
