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Infectious Disease Alert Updates
Corporate Antibiotic Stewardship; Hypervirulence Meets Antibiotic Resistance — A Lethal Combination; Glue Masquerading as an Aortic Root Abscess; Molecular Diagnostic Coup
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California and Coccidioidomycosis: Be Careful About the Air You Breathe
Cases of coccidioidomycosis significantly increased in 2016.
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Polyneuropathy and Nutrition
Other than the identification of a specific vitamin or essential element deficiency, overall nutritional status does not appear to play any role in the development of idiopathic neuropathies in adults.
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Delafloxacin (Baxdela®)
Delafloxacin is a new broad-spectrum fluoroquinolone that was approved by the U.S. Food and Drug Administration in June 2017 for acute bacterial skin and skin structure infections.
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Lamotrigine for Myotonia
SYNOPSIS: In a randomized, double-blind, placebo-controlled treatment trial of patients with non-dystrophic myotonia, those treated with lamotrigine experienced significant improvement.
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REM Sleep, Not Slow-wave Sleep, Decreases Dementia Risk
In a series of clinical studies of cognitively normal people older than 60 years of age, disruption of REM sleep and reduced quantity of REM sleep increased the risk of developing Alzheimer-type dementia.
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Tau as a Biomarker of Acute and Chronic Traumatic Brain Injury
The ongoing search for reliable biomarkers of traumatic brain injury repeatedly has demonstrated the reliability of using plasma phosphor-tau levels to help distinguish injury from normal, and severe injury from mild injury.
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Fungal Endophthalmitis: Another Risk Associated With Intravenous Drug Use
A retrospective cohort study found that endogenous fungal endophthalmitis is associated with intravenous drug use and frequently results in poor visual outcomes despite appropriate surgical and antifungal therapy.
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Taste, Smell, and the Insular Cortex
Olfaction and taste appear to be localized in the insular cortex with bilateral representation.
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Rheumatic Heart Disease — The Global Situation
With advances in access to good medical care, the global burden of rheumatic heart disease is declining. However, there still is significant disease in resource-limited regions of the world.