Articles Tagged With:
-
Caring for Providers: Mindfulness for Healthcare Practitioners
Preliminary studies show some promise for use of mindfulness interventions in healthcare practitioners, but the time required for training medical providers in these techniques is identified as a limitation to implementation.
-
How Many Personnel Are Required for Antimicrobial Stewardship? More Than You Have at Your Hospital
A work group in the Veterans Administration determined that the necessary staffing of antimicrobial stewardship programs dealing with inpatients (including long-term care) is 1.0 clinical pharmacy specialist with infectious disease knowledge and 0.25 physician (preferably trained in infectious disease) per 100 occupied beds. Needs for outpatient stewardship, which is now mandated, were not included in the assessment.
-
Treatment of Pulmonary Mycobacterium avium Infection: Failure Is Common
Current treatment regimens for pulmonary Mycobacterium avium infection leave a great deal to be desired.
-
Immunohistochemistry and Diagnosis of Viral Diseases
Researchers reviewed five years of cases at an academic medical center’s pathology department for the use of immunohistochemistry to detect CMV, HSV-1, HSV-2, varicella zoster virus, adenovirus, or polyomavirus. Of 957 cases, 134 were positive. Viral cytopathic effect (CPE) was present on hematoxylin and eosin staining in 75% of the IHC+ cases. No changes in clinical care occurred in any of the IHC+ cases in which viral CPE was absent.
-
Mice, Mutations, and Microcephaly: The Evolving Pathogenesis of Congenital Zika Syndrome
Approximately five years ago, a single gene mutation altered Zika virus, making it able to target neuronal progenitor cells and cause what we now know as congenital Zika syndrome with microcephaly and ocular abnormalities.
-
Angiotensin II Raises Blood Pressure in Patients with Vasodilatory Shock
The ATHOS-3 trial represents an important proof of concept trial regarding angiotensin II as a new vasopressor in the armamentarium to treat vasodilatory shock.
-
Antibiotics and Adverse Events: Doctors, Do No Harm
A retrospective study found that among 1,488 hospitalized patients who received an antibiotic, 298 (20%) experienced at least one antibiotic-associated adverse drug event. Furthermore, 287 (19%) of the antibiotic regimens were not clinically indicated, and 56 (20%) of these were associated with an adverse drug event.
-
Natriuretic Peptide-guided Therapy Does Not Improve Systolic Heart Failure Outcomes
A recent meta-analysis of 11 trials showed a significant reduction in all-cause mortality with natriuretic peptide-guided therapy, although the individual trial results varied substantially.
-
Is a Dabigatran Reversal Agent Effective?
Dabigatran is an attractive oral anticoagulant for patients who demonstrate indications for oral anticoagulation but are at high risk of bleeding.
-
Defense Verdict in 11-Year Delay-in-Diagnosis Case
At first blush, this is a relatively straightforward failure-to-diagnose case, but the essence of this case is that the patient’s cancer would not have been cured in 2004 if the physician had made the proper diagnosis and followed up appropriately, resulting in a defense verdict.