Articles Tagged With:
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How to Ensure Exempt Studies Maintain Data Confidentiality
Whether the Common Rule changes requirements for handling exempt studies, IRBs might choose to stay involved in these decisions. How they accomplish that depends on the IRB’s policies, procedures, and goals, but one important focus should be on data confidentiality.
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Soft Tissue Disorders of the Neck in Children
Pediatric patients frequently present to the emergency department with issues affecting the soft tissues of the neck. This article will focus on the assessment, evaluation, differential, and treatment of both superficial and deep neck soft tissue disorders that clinicians should consider in the emergency setting.
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Clinical Trials Often Exclude Women, Even When There Could Be Compelling Benefit
Clinical trials often exclude pregnant women, citing additional risks. However, women almost never are asked what they think about participating in those studies and the risks. This is an issue some researchers are working to correct.
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Revisiting the ‘Unfortunate Experiment’ in New Zealand
It’s astonishing in retrospect that women in New Zealand diagnosed with an increasingly clear precursor to cervical cancer were left untreated and uninformed in an unethical study that continued for two decades.
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Clinical Briefs
In this section: considering cardiorespiratory fitness and mortality; searching for answers on knee osteoarthritis; and comprehensive treatment for atopic dermatitis.
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Abemaciclib Tablets (Verzenio)
Abemaciclib is indicated in combination with fulvestrant for the treatment of women with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic breast cancer with disease progression following endocrine therapy.
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Cardiac Stenting No Better Than Aggressive Medical Management for Stable Angina and Single Vessel Disease
Investigators conducted the first blinded, randomized trial comparing percutaneous coronary intervention with medical management.
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Migraine With Aura, Stroke Risk, and Biomarkers
The authors of a longitudinal cohort study of twins found no increased stroke risk related to migraine overall, but there was a modestly increased risk for stroke related to migraine with aura. Familial factors and vascular biomarkers associated with migraine with aura may explain its correlation with vascular disease.
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Procalcitonin to Guide Antibiotic Therapy for Acute Respiratory Infections
The authors of this meta-analysis reviewed patient-level data on 6,708 patients from 26 randomized studies that examined procalcitonin-directed antibiotic therapy for acute respiratory tract infections. They found a 1% reduction in mortality and a 2.4-day reduction in antibiotic exposure for the procalcitonin-directed therapy groups. How procalcitonin can be incorporated into routine clinical practice, in what settings, and whether it is cost-effective are still unclear.
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Most Clinicians Admit to Sharing EMR Passwords
A majority of medical staff surveyed recently said they have accessed an electronic medical record (EMR) system using a password improperly supplied by a fellow medical staffer, and explained that strict confidentiality rules can make it difficult to get the data needed to do their jobs properly.