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The Opioids Just Keeping Coming
Most opioid prescriptions are continued after a patient overdoses accidentally. Those patients are also at risk for a recurrent overdose.
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Overdiagnosis of Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension is over-diagnosed because of a lack of physician expertise in performing accurate ophthalmoscopy. When considering the diagnosis, referral to a neuro-ophthalmologist is strongly recommended.
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Isolated Dizziness and Vertigo Are Rarely Caused by Stroke
The rate of stroke in patients discharged from the ED with a diagnosis of peripheral vestibular disorder is extremely low, and unless there are associated neurological symptoms and signs, there is no need for extensive ED evaluation.
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Tranexamic Acid-associated Seizures: Features, Mechanisms, and Treatment
Tranexamic acid is a commonly used antifibrinolytic drug that has been associated with increased risk of postoperative seizures. The authors reviewed the incidence, risk factors, and clinical features of these seizures, as well as potential mechanisms. They also proposed treatments and interventions for preventing Tranexamic acid-related seizures.
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Does Rivastigmine Prevent Falls in Parkinson’s Disease?
A randomized, double-blind, placebo-controlled Phase II clinical trial of oral rivastigmine in 130 patients with moderate-stage Parkinson’s disease demonstrated improved gait stability as measured by accelerometry, and suggested an association with lower rate of falls.
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Intraoperative Neurophysiologic Monitoring: Does it Change the Outcome from Spinal Surgery?
In non-complex spine surgeries (spinal decompression and spinal fusion), intraoperative neurophysiologic monitoring improved clinical outcomes and reduced the risk of neurological complications by nearly one-half (49%).
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Sonographic Diagnosis of Inclusion Body Myositis
Inclusion body myositis has remained a clinical diagnosis assisted by a muscle biopsy, but now muscle ultrasound and biomarker identification may aid diagnosis.
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Potatoes Increase Risk of Type 2 Diabetes Mellitus
Potato consumption, particularly in the form of French fries, is strongly correlated with the development of type 2 diabetes.
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Perils of High-dose Vitamin D Supplementation
Bischoff-Ferrari H, et al. Monthly high-dose vitamin D treatment for the prevention of functional decline. JAMA Intern Med 2016; doi:10.1001.
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Chinese Herbal Medicine for Esophageal Cancer
Although Chinese herbal medicine probably does not slow disease progression or improve survival in esophageal cancer patients, it may improve quality of life and reduce adverse effects of radiotherapy and chemotherapy.