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Deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus is an effective procedure that markedly improves quality of life in patients with medication-refractory essential tremor. An initial wave of enthusiasm greeted the approval of DBS, but concerns have been raised about its long-term efficacy and the risks of hardware failure and infection. To address these questions, a consortium of neurologists set out to enroll patients in a longitudinal clinical trial with long-term follow-up.
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Crowther and associates reported the results of a prospective, randomized, controlled study of the use of 2 intensities of warfarin anticoagulation for prevention of thrombosis in patients with the antiphospholipid antibody syndrome who had previous thrombosis.
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The management of blood pressure in the acute phase of ischemic stroke is not well understood. In fact, it has been advocated by some that the pharmacologic elevation of blood pressure may augment perfusion to the ischemic penumbra and improve stroke outcome.
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Neuropathic pain, specifically allodynia following peripheral nerve injury, is a poorly understood phenomenon that challenges clinicians and patients. Tsuda and associates report on animal data that may reveal insights into the underlying mechanism of tactile allodynia.
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Amyotrophic lateral sclerosis (ALS) is a clinical diagnosis made with a high degree of accuracy (> 90%) by physicians familiar with the disease. No test is diagnostic for ALS.
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Practice Parameter for Guillain Barré Syndrome; Symposium on Dementia
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The FDA has approved Pfizer's eplerenone (Inspra) for the treatment of congestive heart failure (CHF) in patients who have sustained a myocardial infarction.
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Some of the key aspects of the Joint Commission on Accreditation of Healthcare Organizations 2005 infection control standards are summarized here:
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The Centers for Disease Control and Prevention (CDC) provides the following answers to some of the most frequently asked questions about community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA).
