-
Synopsis: Delays in ACL reconstruction in patients younger than 14 years old results in more unrepairable meniscus injuries.
-
Synopsis: By using a pertubation training regimen, Chmielewski and colleagues were able to alter muscle contraction patterns in a way beneficial to coping with an ACL-deficient knee.
-
Synopsis: The type of fixation device used in an anterior cruciate ligament reconstruction determines the strength and stiffness of a tendon in a bone tunnel following implantation.
-
Synopsis: Custom biomechanical orthoses are beneficial in reducing the risk of stress fracture for walking, especially in army boots; however, these orthoses are not helpful in activities that involve running or when athletes are already wearing standard running shoes.
-
-
Within minutes of an acute cerebral ischemic insult, diffusion-weighted magnetic resonance imaging (DWI) demonstrates ischemic regions with a decline in the apparent diffusion coefficient (ADC) of water. ADC decline is associated with impaired high-energy metabolism and loss of ion homeostasis. Animal studies and preliminary observations in humans demonstrate that initial DWI and ADC abnormalities are reversible by early reperfusion.
-
Among patients with coronary artery disease, HMG CoA reductase inhibitors (statins) are a mainstay of therapy. These drugs have also become widely prescribed with a low threshold to patients with elevated cholesterol and even minimal cardiac risk factors.
-
Intravenous immunoglobulin (IVIG) is safe and effective therapy for acute exacerbations of myasthenia gravis (MG), myasthenic crisis, and for optimizing patients conditions in preparation for thymectomy. Its role in the long-term management of MG remains to be defined.
-
Among patients undergoing epilepsy surgery for pharmacologically refractory seizures, detection and excision of a structural lesion congruent with the electroencephalographic ictal onset is a strong predictor of a seizure-free outcome.
-
Overlap of symptomatology can make differentiation of myasthenia gravis (MG) from Lambert Eaton myasthenic syndrome (LEMS) challenging. Among 101 patients with MG and 38 with LEMS, clinical features allowing more accurate differential diagnosis are noted.
