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Results of the SELECT trial, a large randomized, placebo-controlled, double-blind trial designed to help determine whether selenium, vitamin E, or both could safely prevent prostate cancer in middle-aged and older men, were not to be published for another four years. Interim analyses, however, revealed no benefit from therapy, and even some potential health concerns.
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This article was a systematic review and meta-analysis of high-quality randomized controlled trials determining the effect of fiber, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome, and demonstrating superiority of the three examined therapeutic modalities as compared to placebo.
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Margarines containing plant sterols and stanols can be an effective long-term therapeutic intervention to aid with cholesterol lowering in people already on a stable statin regimen.
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Osteoarthritis is the most common form of arthritis and a leading cause of disability in the United States.
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Carnitine supplementation produced beneficial changes in endothelial function as measured by flow-mediated dilation (FMD) after a high-fat meal. No significant differences were found for other biomarkers of inflammation and oxidative stress.
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A well-regarded, standardized extract of Ginkgo biloba does not appear to help prevent development of dementia in seniors with baseline normal or mildly impaired cognitive function. Whether use of ginkgo earlier in life has a primary preventive effect on development of dementia remains to be determined.
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Approximately 38% of adults in the united states aged 18 years and older and nearly 12% of U.S. children aged 17 years and younger use some form of complementary and alternative medicine (CAM), according to a nationwide government survey conducted in 2007.
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Mathematical models (a case reproduction number/stochastic model and a long-term epidemic dynamics/deterministic transmission model) were used to explore the effect of testing for all people 15 or older for HIV and initiating ARV therapy immediately after diagnosis.
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A retrospective study at a tertiary pediatric hospital in Israel of all children with a positive blood or synovial fluid culture for K. kingae during 1996-2006 revealed 62 children with invasive K. kingae infections. Of these, 42 (68%) had positive blood culture results and 20 (32%) had positive synovial fluid cultures. There were no cases of osteomyelitis documented.
