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Evaluation of a large United Kingdom (UK) database supports a dose-related association with hip fracture. There appears to be a correlation between PPI use, including dosage and chronicity, and occurrence of hip fractures in patients over age 50.
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The FDA has approved a new atypical antipsychotic agent. Paliperidone is the active metabolite of risperidone. The drug is formulated in an osmotic drug delivery system (OROS) developed by ALZA.
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The Finnish Diabetes Prevention Study (FDPS) demonstrated that a program of diet and exercise was capable of reducing the incidence of diabetes by approximately 60% in persons with impaired fasting glucose (IFG) or impaired glucose tolerance (IGT), compared to placebo.
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Searching Google yielded a correct diagnosis in greater than half of cases.
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In a recent paper, Walker and McDowell contacted 1200 patients having had this procedure since 1996 at either the Royal Surrey County Hospital or the London clinic. One hundred eight women had tried to become pregnant and 33 succeeded at least once. In total, the authors had data on 56 completed pregnancies.
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Women with pathogenic mutations in BRCA1 or BRCA2 are known to be at substantially higher lifetime risk for ovarian and breast cancer than the general population. The degree to which reproductive factors affect this risk has been estimated but is limited by studies of small sample size or faulty methodology.
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These Iranian investigators randomized treatment of 108 patients with unruptured ectopic pregnancy to either a single dose protocol or a multiple dose protocol. The single dose regimen was successful in 48/54 cases (88.9%), while 92.6% (50/54) patients responded to the multiple-dose regimen.
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The investigators enticed 14 male surgeons and 16 male physicians (internal medicine and sub-specialists) to submit recent photographs of themselves to the investigators and to indicate how tall they were.
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Herbal Supplements to Treat Vasomotor Symptoms; Bisphosphonates to Treat LBD, After 5 Years?; FDA Actions