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Richards and colleagues representing the Canadian Multicentre Osteoporosis Study Research Group reported the effect of daily selective serotonin reuptake inhibitors (SSRIs) use in a prospective cohort study in 7 regional centers of 5008 adults over the age of 50.
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Ovarian cancer patients relapsing within 6 months of their primary therapy represent among the most challenging patients to treat. Generally, in this setting, most patients have only been exposed to one or two agents, yet they are phenotypically resistant to most chemotherapeutics, making drug discovery of paramount importance.
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Results of the Women's Healthy Eating and Living (WHEL) study were published in a recent issue of JAMA. In this multicenter, randomized controlled trial a total of 3088 women diagnosed with early-stage breast cancer (stage I-IIIa) within the previous four years were randomized to a diet rich in vegetables, fruit and fiber and low in fat, vs a regular diet.
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Older women taking SSRIs had higher rates of hip bone loss compared to both nonusers and TCA users, when measured twice over an average of 5 years.
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Although anti-reflux surgery seems to be declining in the United States, there are still many such operations undertaken. However, new data make it clear that very few patients are candidates for fundoplication.
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After a positive coronary CT scan, patients often undergo stress myocardial perfusion scanning, but the relationship between these two tests in relation to prognosis is poorly understood.
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The FDA has approved a humanized monoclonal antibody for the treatment of paroxymal nocturnal hemoglobinuria (PNH).
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Liver fibrosis from chronic hepatitis C is worse after menopause and less severe in women receiving hormone therapy.
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Disturbance of sleep continuity, but not simple sleep deprivation, impairs pain inhibition and increases spontaneous pain.
