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Germline mutations in BRCA1 or BRCA2 associated with the Hereditary Breast/Ovarian Cancer syndrome have an increased lifetime risk for breast (up to 85%) and ovarian (up to 46% BRCA1, up to 27% BRCA2) cancer.
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A team of epidemiologists from several institutions in the US performed a case-control study of the association between oral contraceptive use and lobular and ductal breast cancer occurring in young women (under age 44).
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Wilkinson and colleagues from the University of Texas in Galveston analyzed information from the Surveillance, Epidemiology, and End Results (SEER) databank linked to Medicare claims.
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In a study of 82 patients with primary dysmenorrhea who had been randomized to undergoing either LUNA or LUNA + PN, the two groups had comparable results (69% improved in the LUNA group; 73% in the LUNA+PN group) at up to 12 months of follow-up.
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In this issue: Updated Immunization Guidelines from the CDC; Do antivirals have a role in the treatment of Bell's palsy? Topiramate is a promising treatment for alcohol dependence; and FDA Actions.
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Use of statins is associated with reduced rate of deterioration of lung function with aging, though the effect is reduced in those who continue to smoke.
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Exceptional attention has been paid to the recent publication of the COURAGE Trial (April 2007) regarding the efficacy of percutaneous coronary intervention (PCI) in stable coronary disease patients.
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The FDA has approved a new antimicrobial agent from the carbapenem class. Carbapenems are broad spectrum, beta lactam, antimicrobial agents.