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Women aged 24-45 years with no history of genital warts or HPV-related cervical disease received either the quadrivalent HPV vaccine (n = 1911) or placebo vaccine (n = 1908) in a multicenter, international, parallel group, randomized, placebo-controlled, double-blind study.
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The standard surgical approach to ovarian cancer in medically fit patients is extirpation of the uterus, tubes, and ovaries, along with systematic staging or debulking of metastatic disease.
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A survey of U.S. primary care physicians found that although most recommend weight loss to their obese patients, they do not utilize current evidence-based recommendations, and they underestimate the therapeutic effects of small weight losses.
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Brown adipose tissue is involved in temperature regulation, and relates to metabolic rate and body mass index. Its activity appears to be reduced in people who are obese.
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Patients with chronic heart failure (CHF) report progressively worse dyspnea with exercise, ranging from Class I NYHA (symptoms only present with strenuous exercise) to Class IV NYHA (symptoms present with any activity, even at rest).
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Despite a clear-cut association between asthma and gastroesophageal reflux, aggressive PPI treatment had no clinical effect on poorly controlled asthma.
