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A retrospective study was conducted on members of one family following the deaths of a 15 year old boy and his 13 year old sister. Airway, CSF and serum samples were collected from the two fatal cases. Serum was collected from the three remaining ill siblings and both parents.
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In this issue: Drug shortages; metformin and cancer prevention; migraine prevention guidelines; and FDA actions.
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Ray and colleagues examined the risk of cardiovascular death among patients 30 to 74 years of age enrolled in the Tennessee Medicaid program that had been prescribed azithromycin between 1992 and 2006.
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In an effort to reduce unnecessary testing, these investigators performed a retrospective observational study of 671 TEE-guided direct current cardioversions (DCC) for atrial fibrillation (AF) to evaluate the indications used for TEE and the outcomes with regard to thromboembolism post DCC.
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Early surgery for infective endocarditis (IE) has been supported by several observational studies, but the lack of randomized, controlled data has led to conflicting recommendations by major societies.
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atients with diabetes mellitus (DM) are at increased risk of developing acute coronary syndromes (ACS). Furthermore, after hospitalization with ACS, patients with DM are at increased risk of suffering repeat hospitalization for ACS. In recent years, a number of trials have tested the strategy of routine early invasive approach (i.e., diagnostic angiography with a view to revascularization) vs an early conservative strategy (i.e., medical management with coronary angiography only performed in cases of refractory ischemia).
