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This paper reports the early results from a proof-of-concept study looking at combined renal artery denervation and pulmonary vein isolation in hypertensive patients with atrial fibrillation. The authors randomized patients with drug refractory atrial fibrillation and drug-resistant hypertension to either standard pulmonary vein isolation or pulmonary vein isolation with renal artery denervation in a single procedure.
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Drug-eluting stents (DES) reduce the rate of in-stent restenosis (ISR) compared to bare-metal stents (BMS). However, the first-generation DES had higher rates of late stent thrombosis than BMS, and this was more evident after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI).
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The use of non-steroidal anti-inflammatory drugs (NSAIDs) early after myocardial infarction (MI) has been shown to increase the risk of death or recurrent MI, but little is known about the long-term risks.
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The left atrial appendage is thought to be the source of a large proportion of emboli in patients with nonvalvular atrial fibrillation. In this paper, Bartus and his colleagues describe an innovative new device that uses a combined transseptal-epicardial approach to ligate the left atrial appendage.
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Menopausal hormone therapy and risk of VTE and AD; patients' understanding of chemotherapy benefits; and FDA actions.
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This retrospective study of all non-psychiatric patients admitted to an academic medical center found that although those placed in contact isolation from the time of admission had no increased risk for delirium, patients moved into isolation after admission were twice as likely to develop delirium during the hospital stay.
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These studies support inclusion of beef in heart-healthy diets.
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A new topical preparation for the treatment of head lice has been approved by the FDA. Ivermectin is a macrocyclic lactone antibiotic that has been used orally both on and off label for head lice since 2001. This new formulation is a topical lotion (oral invermectin is not approved in the United States). It is manufactured by DPT Laboratories and is distributed by Sanofi Pasteur, Inc., as Sklice.
