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The interpretation of tuberculin skin tests (tst) is challenging and controversial, especially in the face of previously administered BCG vaccine. In Switzerland, a country where TB infection is not common but where BCG had previously been routinely given, Zysset and colleagues prospectively evaluated 2- step (second test done 8-15 days after the first for possible booster effect) TST results in 5117 hospital employees, in view of potential risk factors for TB infection.
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Anemia of Chronic Disease (ACD) is a common disorder occurring in patients with acute and chronic inflammatory conditions. ACD is associated with infectious diseases, as well as with malignancies and autoimmune disorders. The pathophysiology of ACD involves abnormalities in iron homeostasis, impaired erythropoiesis, and blunted responses to erythropoietin, brought about by mediators of inflammation such as TNF-alpha, interferon-gamma, and interleukins.
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In 1967, in marburg, a medieval university town north of Frankfurt, Germany, on the Lahn River, several employees of a Behringwerke AG, a manufacturer of vaccines, were hospitalized at the University Medical Clinic with a severe influenza-like illness.
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This article evaluates a mass immunization program with recombinant cholera-toxin B subunit, killed whole cell (rBS-WC) cholera vaccine in Beira, Mozambique, a city where seroprevalence of HIV infection is 20-30%.
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In vitro resistance to daptomycin associated with clinical failure during treatment for MRSA infection has not been well documented. In vitro resistance to daptomycin is uncommon, de novo-resistant clinical isolates have not yet been reported, and the incidence of resistance, occurring during treatment is believed to be very low. The mechanism of resistance is not even known.
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Is Holding NSAIDs Prior to Surgery Rational?; Low-Dose Aspirin: Men vs Women; FDA Actions
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In this study from Rush University Medical Center in Chicago, Duckro and colleagues carried out a careful molecular epidemiologic study of the transmission of vancomycin-resistant enterococci (VRE) to the hands of health care workers from both intact skin areas of VRE-colonizes patients and various environ mental surfaces in the patients vicinity.
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Leonard and colleagues reviewed all the sputum specimens obtained to test for tuberculosis for nearly 4 years in a large public teaching hospital. Sensitivities of first, second, and third acid-fast bacilli (AFB) smears were calculated overall and also separately for HIV-negative and HIV-positive patients.
