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Delirium occurred in about one-third of patients in this study of a mixed medical-surgical ICU population. It was more frequent in more seriously ill patients, and also in those with hypertension, alcoholism, and the effects of sedative and analgesic drugs.
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Vancomycin was inferior to cefazolin in the treatment of MSSA bacteremia in chronic hemodialysis patients in a retrospective study.
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Aspirin can be life saving in patients with acute coronary events, but its use in patients with cancer, particularly in those with thrombocytopenia, is often avoided, presumably for fear of hemorrhagic complications.
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Status epilepticus, in the setting of cancer, is treatable and does not appear to increase mortality above the risk of the underlying disease.
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The clinical presentation of PLS and ALS are similar, and it may be difficult to distinguish them early in the course.
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Surgery for frontal lobe epilepsy can be very effective in patients with a localized ictal onset zone, focal MRI abnormalities, nocturnal epilepsy and complete resection of the epileptic zone and/or imaging abnormality.
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Selected patients with anticoagulation-associated intracerebral hemorrhage may benefit from surgical evacuation.
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Two recent large studies have looked at the effects of various inhaler combinations on outcomes in patients with COPD.
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New combination chemotherapy protocol for malignant glioma improves 6-month progression-free survival for a dismal disease.