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FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.
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Telcagepant, a new oral calcitonin gene-related peptide receptor antagonist, has similar efficacy and better tolerability for acute migraine headaches as compared to a triptan.
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Sleep disordered breathing occurs in most acute stroke patients and may contribute to morbidity
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Great progress has been made in identifying the underlying genetic defects in congenital myopathies.
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Chronic treatment with warfarin, prior to presentation with an ischemic stroke, is associated with a significant decrease in infarct size.
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The ACC/AHA guidelines recommend perioperative beta blockers for those already on them, patients undergoing vascular surgery, or those having intermediate- to high-risk surgery with established coronary heart disease, or at high risk of having it. However, recent studies have shown no beneficial effect of perioperative beta blockers and potential for harm.
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Optimal management of transmural myocardial infarction (MI) depends on rapid reperfusion of the occluded infarct artery. Therefore, accurate early diagnosis is the cornerstone of initial patient assessment in the emergency department.
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In this large epidemiology study using a previous survey and 2004 Medicare data focusing on serious infections in the ICU, hospitals with dedicated ICU clinical pharmacists had lower ICU mortality rates, shorter ICU stays, and reduced charges.
