In this issue: Tamoxifen and CYP2D6 inhibitors, FDA Actions, and FDA
Warnings.
HOPS is an ongoing prospective, observational cohort study of HIV-infected patients at 10 participating HIV clinics in the United States. A total of 2,699 patients with HIV RNA > 1,000 copies/uL were seen from 1999-2005. Demographic characteristics, clinical factors, and GPT use were correlated with all-cause mortality.
In order to reduce the rate of catheter-related bloodstream infections (CRBSIs) in intensive care units, Northwestern Memorial Hospital implemented patient care bundles in all ICUs in August 2005.
Neuropsychiatric side effects and sleep disturbances are among the more prominent and limiting features of efavirenz (EFV) therapy for HIV infection.
Surgery may offer pain relief for selected patients with specific headache types, such as migraines with trigger sites and Chiari I malformation related headaches.
Tinel's test, flexion compression, and ulnar nerve palpation in patients with ulnar neuropathy must be interpreted with caution, but omitting them and saving time doesn't appear to impact diagnostically.
