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The TNT study (Treat to New Targets) demonstrated that intensive lipid lowering (ILL) with atorvastatin 80 mg/d in patients with stable coronary artery disease (CAD) provided more benefit than simply achieving an LDL of 100 mg/dL with atorvastatin 10 mg/d.
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An MRI is often used to assist in the diagnosis of multiple sclerosis. This systematic review of 29 studies shows that an MRI will result in an overdiagnosis of MS when used after one episode of neurologic dysfunction.
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A 12-lead ECG was obtained from a 66 year old man with heart failure. How would you interpret this ECG? Does the patient have RBBB (right bundle branch block)? Is there "a twist" to answering this question?
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Do long-acting beta agonist inhalers increase the severity of asthma? Yes, according to the results from a large meta-analysis recently published in the Annals of Internal Medicine.
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Rescue PCI in the setting of early fibrinolytic failure improves mortality, but this is tempered by a possible increase in the risk of thromboembolic stroke.
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Even a device which makes perfect physiological sense may not help us achieve the goals of improved outcomes for out-of-hospital cardiac arrest victims.
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Commonly used drugs in patients with coronary disease or COPD may be beneficial in the absence of specific guideline recommendations at present.
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Do long-acting beta agonist inhalers increase the severity of asthma? Yes, according to the results from a large meta-analysis recently published in the Annals of Internal Medicine.
