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In a previous study involving patients in a surgical ICU1, Van den Berghe and associates at the Catholic University of Leuven, Belgium, showed that tight control of serum glucose levels by means of a strict insulin infusion protocol decreased both morbidity and mortality.
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This study examined the effect of variations in ICU staffing, defined in terms of intensivist-to-ICU bed ratio, on ICU length-of-stay (LOS) and ICU and hospital mortality. The study was conducted at the Mayo Clinic in Rochester, MN over a 9-month period when the medical ICU underwent a series of planned changes which resulted in its capacity increasing from 15 to 24 beds.
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The Institute of Medicine has documented that the hospitaland the ICU in particularis an environment in which errors are all too frequent.
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Long-Term Effects of Warfarin Use; Statins Multiple Benefits; FDA Actions
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Samples obtained by swabbing both nares of almost 10,000 individuals > 1 year of age in the US National Health and Nutrition Survey (NHANES) in 2001-2002 were cultured on mannitol salt agar. S. aureus was identified in 32.4% of subjects and 0.8% were colonized with methicillin resistant S. aureus(MRSA).
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Adverse drug events (ADES) are unwanted consequences of drug therapy and have important implications for each patient, the treating physician, and the institution itself. When assessing adverse effects, prescribing healthcare workers should pay particular attention to ADEs that interrupt the patients therapeutic regimen and hence increase the patients length of stay in the hospital.
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The first article reports the results of an industry-sponsored clinical trial comparing TDF/ABC/3TC vs EFV/ABC/3TC in treatment-naïve patients. Three hundred forty patients were randomized. Baseline characteristics including CD4 count and HIV RNA level were similar between the arms.
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Tuberculin skin testing is a crude procedure, fraught with potential error at every step, from application to interpretation, and requires 2 visits to a health care provider. Its use has persisted, nonetheless, because it remained, until recently, the only means of detection of latent infection with Mycobacterium tuberculosis.
