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Statins and liver function; dosing timing for thyroxine; rivaroxaban for VTE, DVT, and stroke; echinacea and the common cold; and FDA actions.
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Patients taking dual anti-platelet therapy (DAPT) with aspirin and clopidogrel are at higher risk of bleeding with coronary artery bypass graft surgery (CABG) than those taking aspirin alone.
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The efficacy of statins in preventing cardiovascular events is well known, but approximately 10% of patients will develop elevations in liver function tests (LFTs).
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This paper analyzes data from the national icd registry, which tracks ICD implantations for the primary prevention of sudden death in the United States.
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The results of this well-done study suggest that a specific formulation of echinacea may offer modest benefit to people with the common cold, but that such benefit is statistically, and likely clinically, insignificant. Data from the trial relating to physician-patient interaction and clinical response have yet to be published.
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Findings of this ground-breaking randomized controlled trial suggest that patients with irritable bowel syndrome who receive treatment with placebo tablets, and who are fully aware that they are taking a placebo, have significantly greater relief of symptoms compared with patients who receive no treatment at all. Accessing the placebo effect may not require deception at all.
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Glucosamine sulfate continues to grow in popularity as a treatment for osteoarthritis. Global sales reached almost $2 billion in 2008, an increase of 60 percent over the previous five years.
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An evaluation of medical research by the IOM establishes new RDAs for vitamin D (600-800 IU) and calcium (700-1300 milligrams).
