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A new orally administered macrocylic antibiotic has been approved by the FDA for the treatment of Clostridium difficile infection. Fidaxomicin is a fermentation product of Dactylosporangium aurantiacum and is marketed by Optimer Pharmaceuticals, Inc., as Dificid.
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It has recently been recognized that type 2 diabetes (DM2) increases risk for osteoporotic fracture, even though it has been demonstrated that DM2 is associated with a paradoxical increase in bone mineral density (BMD) compared to age-matched control populations. With a burgeoning prevalence of DM2 in the United States, almost 20% of the at-risk population for osteoporotic fracture has DM2, hence, clarification of risk stratification for this group is highly relevant.
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Scenario: Interpret the rhythm strip shown above. Does it represent 2nd degree AV Block, Mobitz Type II? Clinically â why is it important to distinguish between Mobitz I and Mobitz II 2nd degree AV block?
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Osteoporosis is a highly prevalent metabolic bone disease that affects both men and woman at risk of bone demineralization.
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With the advent of new vaccines, the incidence of bacterial meningitis has declined, particularly in children, but the mortality rate has remained the same.
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Variant Creutzfeldt-Jakob disease usually presents with subtle psychiatric symptoms and there is usually a significant delay in diagnosis.
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Patients originally on interferon beta-1a in the TRANSFORMS study were re-randomized to either 0.5 or 1.25 mg of fingolimod. There was a reduction in relapse rate and MRI activity in patients that switched to fingolimod without an increase in severe adverse events.
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