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While a number of antiretroviral agents have been implicated in contributing to both insulin resistance and lipid abnormalities, HIV also directly causes metabolic disturbances.
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A double-blind, randomized, controlled trial conducted by the International Neonatal Immunotherapy Study (INIS) compared adjunctive therapy of human nonspecific polyvalent IgG intravenous immune globulin to placebo in the treatment of newborn infants with suspected or proven sepsis who were also receiving antibiotic therapy.
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Baseline production of PSMa subtypes was examined in 50 PVL-positive methicillin-susceptible Staphylococcus aureus (MSSA) and MRSA clinical isolates using liquid chromatography-tandem mass spectrometry (LC-MS-MS), and these results were compared to a control strain, LAC (USA300). MICs were determined using a broth macrodilution method.
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Outpatients with a diagnosis of either dentoalveolar or periodontal abscess or a diagnosis of gingival inflammatory infiltrates were randomized to receive either moxifloxacin 400 mg daily or clindamycin 300 mg QID, both for 5 days, in a prospective, randomized, placebo-controlled, double-dummy clinical trial design.
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A total of 783 children 6-24 months of age were followed for an entire respiratory season by four experienced otoscopists using pneumatic otoscopy of one ear, randomly selected for each child.
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In recent months, Escherichia coli O104:H4 has infected more than 4,000 people and caused 880 cases of hemolytic uremic syndrome (HUS) in Europe, with the majority of cases reported in Germany and with more recent outbreaks in France and Switzerland. Travelers should implement food hygiene precautions to prevent infection when visiting Europe.
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Using an algorithm based on score and chest X-ray when appropriate, the overall sensitivity for the detection of aortic dissection was 96%.
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This randomized study of low-tidal-volume ventilation during and after cardiac surgery, in comparison to ventilation with tidal volumes of 10 mL/kg predicted body weight, showed no differences in median ventilation time but higher rates of extubation by 6 and 8 hours postoperatively and fewer reintubations in the low-tidal-volume group.
