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Convexal Subarachnoid Hemorrhage and Amyloid Angiopathy

Cerebral amyloid angiopathy is emerging as a major cause of spontaneous intracerebral hemorrhage in the elderly. The authors of this study undertook a careful review of all of the patients in their database over a 9-year period who had spontaneous convexal subarachnoid hemorrhage, and they performed a careful longitudinal analysis of clinical and neuroimaging data.

Consequences of Intracerebral Hemorrhage in Young Adults

Intracerebral hemorrhage accounts for 10-20% of all strokes in North America and Europe, with an overall incidence of 25 cases per 100,000 population annually. In this study, the authors evaluated the long-term survival and recovery of 268 1-month survivors ages 16-49 years to assess the prognosis of intracerebral hemorrhage in the younger group.

Can Dietary Intervention Delay the Onset of Alzheimer’s Disease?

In a prospective study of an elderly population, moderate adherence to the MIND diet was associated with a 53% reduction in the development of Alzheimer’s disease.

Diagnosing POLG-related Diseases

Mutations of the polymerase-gamma subunit in mitochondrial DNA is a common cause of adult mitochondrial syndromes, such as myopathies, encephalopathies, epilepsy, and ataxias.

Prevalence of Rest Tremor in Essential Tremor

Rest tremor is seen in patients with more advanced essential tremor, yet its prevalence varies significantly between patient groups.

Cerebrospinal Fluid Biomarkers of Neuronal Injury in Mild AD

Cerebrospinal fluid visinin-like protein 1 is a useful marker, along with CSF tau and phospho-tau measurements, to predict brain atrophy and neurodegeneration in patients who carry a clinical diagnosis of Alzheimer’s disease.

Serum and CSF Biomarkers of Brain Injury After Sports-related Concussion

ABSTRACT & COMMENTARY: So far none of the currently measured biomarkers has sufficient sensitivity or specificity to be clinically useful.

Obstructive Sleep Apnea

MONOGRAPH: Continuous positive airway pressure devices remain the mainstay of treatment. If CPAP is poorly tolerated, here are your options.

Prevention of Proton Pump Inhibitor-induced Bowel Symptoms with Probiotics

The administration of a Lactobacillus paracasei strain (F19) twice daily and 3 times per week for 6 months appears to reduce the incidence of bowel symptoms (bloating and flatulence) and reduce changes in bowel habits (increased stool frequency and loose stools) but not abdominal pain in patients taking proton pump inhibitors.

Sustainable 25(OH)D Levels? Choose Vitamin D3 over D2

Compared to vitamin D2, daily supplementation with vitamin D3 appears to sustain serum 25(OH)D levels even after discontinuation of supplementation in healthy adults.