Internal Medicine
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Think Twice About That Fluoroquinolone Prescription
The FDA warns that serious side effects associated with fluoroquinolone antibacterial drugs generally outweigh the benefits for certain patients.
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Interval Training for Cardiovascular Health: Less is More?
Sedentary men achieved similar cardiometabolic improvements after 12 weeks of either short-duration, high-intensity exercise or the standard 45 minutes of sustained moderate-intensity exercise.
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Mediterranean Diet and Breast Cancer
A Mediterranean diet supplemented with the consumption of one liter of extra-virgin olive oil per week may be beneficial in the primary prevention of breast cancer.
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The Effects of Coffee Consumption on Health Outcomes
Worldwide, coffee is the second most consumed beverage after water. Chosen because of its rich complex flavors and pleasant stimulating effects, recent research suggests potential health benefits, including risk reductions for cardiovascular disease, cancers, diabetes, and Parkinson’s disease.
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The Pitfalls of Herbal Viagra
Be wary of and avoid over-the-counter products that claim to boost libido and sexual function, particularly for erectile dysfunction, which are often of spurious quality and contaminated with PDE-5 analogues.
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Demyelinating Neuropathies in Children
Electrodiagnostic criteria using nerve conduction velocities are useful to distinguish most hereditary neuropathies from acquired neuropathies in children.
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Mechanisms of Tissue Hypoxia and Cerebral Ischemia in Traumatic Brain Injury
Tissue hypoxia after traumatic brain injury occurs in a widespread manner in the brain, including areas that appear structurally normal. Moreover, cerebral tissue hypoxia appears to occur independent of ischemia with areas of no overlap, implying a microvascular etiology.
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Sleep Disorders Associated with Traumatic Brain Injury
Patients with traumatic brain injuries need longer sleep times to heal the injured brain, and persistent pleiosomnia at 18 months implies that ongoing abnormalities are producing an increased need for sleep.
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Eating Behavior in Frontotemporal Dementias
In a prospective, controlled study of 49 patients with dementia and 25 healthy controls, marked hyperphagia is restricted to behavioral-variant frontotemporal dementia patients that is likely due to differing neural networks, while increased sucrose preference is likely controlled by a similar network in both behavioral-variant frontotemporal dementia and semantic dementia patients.
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Migraine with Aura and Systemic Right-to-Left Shunt: Risk for Stroke?
Right-to-left shunts, as detected by transcranial Doppler, are more common in patients with migraine with aura, but are not correlated with increased risk of silent posterior circulation infarcts or white matter lesions on MRI.