Internal Medicine
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Genital HPV in Men: How Common Is It?
In this U.S. cross-sectional survey, the prevalence of genital human papillomavirus (HPV) infection in adult men was 45%, of which 25% were high-risk subtypes. The overall rate of HPV vaccination among those who were eligible was 11%.
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Dual Antibiotic Therapy Is Not Routinely Necessary for Uncomplicated Cellulitis
A randomized, multicenter, placebo-controlled clinical trial that enrolled patients presenting to emergency departments with uncomplicated cellulitis found the addition of trimethoprim-sulfamethoxazole to cephalexin did not lead to better outcomes.
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Is This 4:1 Flutter?
The rhythm in the figure was diagnosed as atrial flutter with 4:1 AV conduction. Do you agree? How would you confirm your answer?
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Clinical Briefs
In this section: treating hypothyroidism in seniors; revisiting penicillin allergies; and new diverticulitis guidance.
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Sofosbuvir, Velpatasvir, and Voxilaprevir Tablets (Vosevi)
Vosevi is indicated for the treatment of adult patients with chronic hepatitis C infection without cirrhosis or with compensated cirrhosis who are infected with genotype 1, 2, 3, 4, 5, or 6, and have been treated previously with a hepatitis C regimen containing an NS5A inhibitor.
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Eat Right, and Live
An improvement in diet over 12 years in middle-aged nurses and other health professionals resulted in a decreased risk of death.
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Glucose Self-monitoring Not Helpful for Non-insulin-treated Type 2 Diabetes
In this pragmatic randomized trial, self-monitoring blood glucose did not lead to lower hemoglobin A1c levels or improvement in health-related quality-of-life measures.
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Value-based Payments and Primary Care
Over the past two decades, Medicare and commercial payers have increasing linked healthcare payments to quality. These new payment models are broadly referred to as value-based, as payers primarily focus on clinical and financial outcomes of patients rather than simply paying for services in an unsustainable fee-for-service model. This shift provides a unique opportunity for primary care to recapture its place in healthcare delivery as the original advocate for patient-centered care and the center of value. Primary care clinicians can be rewarded with additional revenue for creating efficient care delivery by developing the skill sets to manage value-based care.
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Capsaicin for Painful Diabetic Peripheral Neuropathy
An 8% capsaicin patch relieves pain and improves sleep in patients with painful diabetic peripheral neuropathy.
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Helping Women at Risk for Breast Cancer to Exercise More and Lose Weight
A web- and phone-based intervention led to significant weight loss and a modest increase in moderate-to-vigorous activity in women at risk of breast cancer.