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The following is a summary of selected abstracts from 3 meetings. The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) met in Chicago September 14-17, 2003. The Infectious Disease Society of America (IDSA) met in San Diego October 9-12, 2003. The American Society of Tropical Medicine and Hygiene met in Philadelphia December 3-7, 2003.
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In what may be a harbinger of a changing host preference, it was found that over one-half of cases of malaria in an area of Malaysian Borneo were caused by Plasmodium knowlesi, monkey pathogen. Such cases are likely to go unrecognized because of the great difficulty in distinguishing this organism from Plasmodium malariae by microscopy.
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Ninety-three percent of sputum isolates from a single long-term care facility were resistant to quinolones. Epidemiologic study showed an association with prior receipt of levofloxacin. Strains were closely related by pulsed field gel electrophoresis (PFGE) analysis, indicating patient to patient spread of a resistant clone.
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A large cohort study from Denmark suggests no link between childhood vaccines and type 1 diabetes.
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New-onset leg weakness or numbness is a common cause for neurologic consultation following gynecologic surgery.
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Cardiac surgery may be complicated by ischemic stroke as well as more non-specific cognitive disturbances. Could prophylactic neuroprotective strategies be employed?
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In order to identify risk factors for CNS ischemic complications at presentation and during follow-up, Nesher and associates reviewed the charts of 175 patients with giant cell arteritis diagnosed between 1980 and 2000 at 4 Jerusalem hospitals.
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Olesen and associates report on a phase II study of BIBN 4096 to evaluate the safety and efficacy of a first in class non-peptide, parenteral CGRP-receptor antagonist.
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Breast Cancer and the Use of Statins; Warnings Issued for IBS Drugs; FDA Actions