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Most of the attention on catheter-related bloodstream infections (CR-BSI) in the ICU focuses on central venous catheters (CVC), a bias that likely derives, in part, from the 2002 Centers for Disease Control guidelines which stipulate that arterial catheters (AC) have "low infection ratesrarely associated with bloodstream infections.
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This paper gives the results of the substrate Mapping and Ablation in Sinus Rhythm to Halt Ventricular Tachycardia (SMASH-VT) study. This study was designed to test the hypothesis that early prophylactic catheter ablation in patients with implantable cardioverter defibrillators (ICD) would decrease the frequency of ICD shocks during follow-up.
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This remarkable study is a population analysis of a huge cohort of children in Denmark who were followed, since 1930 or later, for the presence of coronary heart disease (CHD), and had all mandatory annual examinations at schools in Copenhagen.
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An early invasive approach is preferred for higher risk non-ST elevation acute coronary syndromes (NSTE-ACS), but the optimal timing of cardiac catheterization is not clear.
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Doyle and colleagues performed a retrospective study of a large cohort of patients undergoing PCI at the Mayo Clinic from 1994 to 2000, to determine the long-term outcomes of BMS, with a focus on stent thrombosis and ISR.
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The appropriate treatment of infective endocarditis (IE), to avoid embolic stroke, is unclear. Thus, Dickerman and colleagues explored the International Collaboration on Endocarditis Prospective Cohort Study (ICE-CPS) database to define the temporal occurrence of stroke in relation to antibiotic therapy.
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Patent Foramen Ovale (PFO) has been associated with cryptogenic stroke in young individuals, but the association is less clear in older individuals where other causes of stroke predominate.
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Rosiglitazone (Avandia) implicated in yet another study; Prilosec and Nexium not associated with cardiac events; Anastrozole (Arimidex) shown more effective than tamoxifen for treatment of early-stage breast cancer; antibiotics show no effect on sinusitis; FDA actions.
