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Ivermectin is a well-known anti-parasitic medication that has been used for years, with little toxicity to humans.
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Cryptococcal infection has taken another new twist. For years before the HIV epidemic, infection with C. neoformans mostly occurred in immunosuppressed individuals who also had some defined zoonotic exposure, often to birds or pigeons.
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A physician in new York notified relevant county and state public health authorities in August 2009, of a patient from Rochester with suspected dengue, subsequently confirmed by CDC, whose only travel had been to Key West, FL. Confirmation at the CDC included both serum antibody testing and detection of dengue virus serotype 1 in cerebrospinal fluid.
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In the past decade, rapid response teams (RRTs) were broadly implemented to identify and treat patients on medical and surgical wards at risk for catastrophic deterioration and thus prevent death.
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This issue deals with two key topics in the ongoing discussion about how critical care should be organized: rapid response systems (also called medical emergency teams or rapid response teams) for identifying patients not in ICUs who are at risk for life-threatening deterioration, and around-the-clock intensivist staffing in the ICU.
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The use of a rapid response system (RRS), or medical emergency team (MET), has become established as a patient safety measure to ensure early detection of patient compromise.