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Carotid artery stenting is an attractive concept for the treatment of patients with significant carotid stenoses who were at higher risk for carotid endarterectomy, but stroke rates in initial studies were unacceptably high.
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The pravastatin in elderly individuals at risk of vascular disease (PROSPER) trial is a study of statin therapy in high-risk elderly individuals. PROSPER tested the hypothesis that the benefits of statin therapy on cardiovascular disease, stroke, and cognitive decline would be seen in the elderly, which had not yet been rigorously investigated with respect to LDL lowering with a statin.
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Iwai and colleagues evaluated the effects of adenosine in 42 patients who underwent an electrophysiologic study and radiofrequency ablation for recurrent atrial tachycardias.
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The multicenter, unsustained tachycardia trial (MUSTT) was a randomized clinical trial designed to test whether antiarrhythmic therapy guided by electrophysiologic testing would reduce arrhythmic death and total mortality in high-risk patients.
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Sorrentino MJ. Fish oils to lower trigylerides. Altern Med Alert 2002;5(12):141-144.
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Venkatraman M, Assefi N. Ayurveda: General principles and treatment of rheumatoid arthriitis. Altern Med Alert 2002;5(12):144-147.
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La Puma J. Ephedra and adverse events. Altern Med Alert 2002;5(12):147.
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La Puma J. Ephedra for weight loss. Altern Med Alert 2002;5(12):148.