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Subjects with Lesch-Nyhan disease and Lesch-Nyhan variant have significant reductions in brain size in the basal ganglia as well as several cortical areas.
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An outbreak of fungal meningitis and paraspinal infections occurred over the past year due to contaminated methylprednisolone injections.
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Hyperkalemic periodic paralysis has now been well characterized clinically, physiologically, and genetically.
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Wernicke-Korsakoff syndrome, consisting of the triad of mental status changes, ocular motility abnormalities, and ataxia, in the setting of thiamine deficiency, remains a clinical diagnosis.
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This long-term epidemiological study shows an association between glaucoma and Alzheimer's disease.
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Hepatitis C virus (HCV) infection is an important global health issue that affects approximately 184 million people. Conventional therapy for HCV with interferon and ribavirin is associated with high rates of virological failure and severe side-effects.
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TB rates among pre-school aged children in the United States are 32 times higher in foreign-born children and six times higher in U.S.-born children with at least one foreign-born parent, compared to U.S.-born children with U.S.-born parents.
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Autologous CD4+ T-cells modified to delete CCR5 by Zinc-finger nuclease (ZFN) were infused into 12 HIV-infected patients. Cells survived in the circulation of patients and provided some control of viral replication and immune reconstitution after interruption of antiretroviral therapy.
