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Do We Really Know the Optimal Oxygen Target in Patients with ARDS?

In the LOCO2 study, a conservative oxygen strategy with SpO2 goals of 88% to 92% was not shown to improve mortality over a liberal oxygen strategy as hypothesized, but rather was found to have a worrisome signal of increased mortality and increased mesenteric ischemia.

Management of Pulmonary-Renal Syndrome

The role of the intensivist in the management of pulmonary-renal syndrome includes appropriate respiratory support and recognition and management of concurrent infection, hypovolemia, acute anemia, and coagulopathy.

FDA Issues Emergency Use Authorization for Bamlanivimab

While the search for a vaccine continues, the agency adds to the list of stop-gap therapeutics to battle COVID-19.

AMA Prepares for COVID-19 Vaccine with Coding Updates

Laying the administrative groundwork is an important part of ensuring success for administration of an eventual vaccine.

Remdesivir Injection (Veklury)

Remdesivir’s benefit appears to be modest, but may be better for those receiving low-flow oxygen.

Can Chopsticks Carry SARS-CoV-2?

This small study suggests salivary contamination of utensils with SARS-CoV-2 virus can occur. Sharing food and utensils, or using communal food bowls, probably is not a good idea if one is trying to avoid COVID-19.

Possible Aerosol Spread of SARS-CoV-2 in an Apartment Building

Although not definitive, evidence is consistent with aerosol spread of SARS-CoV-2 in an apartment building as a result of transport through the drainage system to apartments directly above.

A Novel Rifabutin-Containing Combination Regimen Eradicates H. pylori Infection

Researchers found a significantly higher eradication rate for H. pylori with a 14-day regimen of rifabutin, amoxicillin, and omeprazole compared to 14 days of amoxicillin and omeprazole.

Race Correction in Clinical Calculations: Is It Time to Reconsider?

Many clinical calculators use race as a predictive variable to assess risk for outcomes. Although most tools assume a genetic disposition for these outcomes, other factors, such as health disparities and other potential confounders, are more likely to be the underlying reasons for any race-related differences in outcomes.

More Is Not Better with Vitamin D Supplementation

A recent study revealed vitamin D levels higher than normal from high-dose supplementation are harmful to bone health.