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Many patients need to take long-term oral anticoagulants (OAC) for indications such as atrial fibrillation (AF) or mechanical prosthetic valves.
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The decision to choose a mechanical or a tissue valve for patients undergoing surgical aortic valve replacement (AVR) is a complex one that involves synthesizing clinical factors such as risk of bleeding, likelihood of reoperation, and patient preference. Increasingly, older patients with more comorbidities are being referred for AVR surgery.
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Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.
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Myocardial perfusion imaging (MPI) refers to the utilization of radiotracers to image regional myocardial perfusion from coronary artery blood flow to the heart muscle. Used effectively, MPI can provide the clinician with a noninvasive technique that yields both important diagnostic and powerful prognostic information regarding the functional significance of anatomic coronary artery disease. MPI can help guide therapeutic decision-making by stratifying patients with respect to future risk for adverse outcomes.
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Although widespread screening mammography has greatly increased the diagnosis of early breast cancer, it has had only a marginal effect on the diagnosis of late-stage tumors and breast cancer mortality.
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The authors concluded that compared to beta-blockers, the risk of angioedema is highest with ACEIs or aliskiren and lowest with ARBs.
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The authors conclude that in a large cohort of older patients with atrial fibrillation, hemorrhage is common during both the first 30 days and subsequent months of warfarin therapy, and is related to risk factors in the CHADS2 score and also to age.
