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In an observational study conducted in Germany of more than 600 anemic cancer patients receiving parenteral iron (ferric carboxymaltose), hemoglobin levels were shown to rise significantly. The iron treatment was well tolerated. Randomized interventional studies are warranted to demonstrate efficacy in terms of physical function and quality of life and safety in this population.
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This paper details the result of a population-based cohort study of all Ontario, Canada, residents older than 66 years of age who began warfarin therapy for atrial fibrillation over an 11-year period. Patients were identified by the authors from data in the Ontario Health Insurance Plan.
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During family discussions, physicians who believe more strongly that life support should be withdrawn are more likely to present the option of comfort care and describe its benefits.
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Zolpidem, a commonly utilized agent for sleep disturbance, is associated with increased fall risk in hospitalized, non-pregnant, non-critically ill patients. Its use for a given patient and its appropriateness within standard order sets should be carefully considered.
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Special Report from the International Stroke Conference: Current Endovascular Interventions for Acute Ischemic Stroke Do Not Result in Better Clinical Outcomes than Intravenous Thrombolysis
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Calcium supplementation in women; type 2 diabetes treatments and pancreatitis risk; treating chronic idiopathic urticaria; rivaroxaban and VTE; and FDA actions.
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Treatment and Outcome after Acute Cervical Artery Occlusion with Stroke; Continuous Transcranial Doppler Insonation Can Determine Recanalization Following Acute Ischemic Stroke; Antithrombotic Therapy Appears to be Safe for Patients with Cerebral Cavernous Malformations
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Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.
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Cholinergic system dysfunction, as measured by short latency afferent inhibition, might contribute to gait abnormality in early stages of Parkinsons disease.