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The ECG above was obtained from a 61-year-old woman. There are a number of abnormal findings on this tracing. How many can you identify? Depending on the clinical history, which of these findings might be cause for immediate concern?
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Clopidogrel and proton pump inhibitors; adverse events with tamsulosin after cataract surgery; new guidelines for persistent pain in the elderly; and FDA Actions.
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A higher intensity of comprehensive disease management for smoking cessation, similar to other chronic diseases, may yield superior results.
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A review of large randomized clinical trials for type 2 diabetes controlling HbA1c as low as 6.5-7.0% showed many consequences, but uncertain benefits. A new approach to type 2 diabetes should include individualized HbA1c targets along with cardiovascular risk reduction reflecting patients' values and preferences, and caution is urged in using these HbA1c values as performance measures to indicate inadequate care.
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A polypill consisting of low doses of thiazide, atenolol, ramipril, simvastatin, and aspirin administered to 2053 subjects in 50 centers in India was effective in reducing multiple risk factors and cardiovascular risk.
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The FDA has approved the first oral, selective vasopressin V2-receptor antagonist for the treatment of hypervolemic and euvolemic hyponatremia.
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The ACTIVE Investigators. Effect of clopidogrel added to aspirin in patients with atrial fibrillation.
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Resistance to antibiotics continues to pose a serious problem in treating infections. While new pharmaceutical agents are being developed, interest in alternative treatments is also growing. Grapefruit seed extract is one commercially available antimicrobial that has attracted considerable attention.
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Several large observational studies have suggested that vitamin E supplementation lowers the risk of coronary heart disease. However, the results of large randomized controlled trials failed to show a clear benefit of a-tocopherol supplementation on cardiovascular outcomes.
