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The FDA has approved the first treatment for relapsed or refractory peripheral T-cell lymphoma. Pralatrexate, an inhibitor of dihydrofolate reductase, was granted accelerated approval by the FDA. It will be marketed by Allos Therapeutics as Folotyn™.
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Headaches are one of the most common problems of patients presenting to primary care physicians. Workup and management can be both frustrating and demanding.
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Depression and pregnancy, new vaccine recommendations from the CDC, cortico-steroids and/or antivirals for Bell's palsy, rasagiline and Parkinson's disease, and FDA Actions.
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A subgroup analysis on elderly Chinese patients with a history of myocardial infarction (MI) revealed beneficial effects of Xuezhikang, a red yeast rice extract. Risk of coronary and all-cause deaths were significantly lowered, total cholesterol and LDL- cholesterol levels were reduced, and HDL-cholesterol levels were increased significantly compared to placebo.
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This survey study assessed religious behavior, affective state, and health behaviors in a group of 167 adult cancer survivors. A measure of religious experience was associated with self-confidence, while religious struggle was associated with feelings of guilt, and all were associated with some health behaviors. After controlling for affective state, associations with the religion variables were no longer statistically significant, though a measurable indirect effect, mediated by affective state, could be detected.
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In a mouse model of atherosclerosis, researchers showed that a low-carbohydrate, high-protein diet with a macronutrient profile that approximates the maintenance phase of well-known low-carbohydrate diets in humans significantly worsens the development and severity of aortic atherosclerosis in the absence of significant changes in well-established biomarkers for cardiovascular disease. In addition, such a diet appears to impair neovascularization in response to ischemia.
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One-third of adults older than age 40 has vestibular dysfunction.
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