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The literature on the technical and clinical aspects of mechanical ventilation for patients with acute respiratory failure continues to expand, with nearly 50,000 citations appearing in PubMed for the topic "mechanical ventilation," and more than a thousand articles in English reporting the results of clinical trials under this heading published during the last 5 years.
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The objective of this study was to evaluate the role of patient-ventilator dys-synchrony in the etiology of sleep disruption, and to determine whether optimizing patient-ventilator interactions by using proportional assist ventilation (PAV) improves sleep.
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Using laboratory results from a recent 30-month period for case finding, Lamontagne and colleagues reviewed the medical records of all patients with fulminant Clostridium difficile-associated disease (CDAD) who received care in the ICUs of 2 tertiary-care hospitals in Quebec.
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GlaxoSmithKline's rosiglitazone (Avandia) will receive a black box warning by the FDA because of concerns over heart failure associated with use of the drug.
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In a pilot study, ten women with liver predominant metastatic breast cancer were treated with intra-hepatic arterial infusion of paclitaxel (200 mg/m2 over 24 hours, monthly).
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Anemia is a common problem associated with increased mortality among older adults. The higher prevalence of anemia in black older adults compared to white older adults has raised concern whether different hemoglobin (Hb) thresholds should differ by race.
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In an analysis of four clinical trials designed to assess the efficacy of two different human papilloma virus (HPV) vaccines, the appearance of pre-neoplastic lesions and neoplastic cervical adenocarcinoma was dramatically reduced in vaccinated subjects.
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