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Moderate-Intensity Exercise OK for Statin Users with Muscle Pain

The go-to drug therapy patients use to lower their bad cholesterol levels can cause muscle pain for some, but researchers found moderate exercise would not exacerbate that pain.

Failure to Report Study Findings in Timely Manner Erodes Public Trust

Further, this can contribute to bias in the scientific knowledge base, limit the ability of future investigators to build on knowledge generated from prior research, and lead to duplication of research efforts and misuse of scarce resources.

Double BBB, or Complete AV Block?

The ECG in the figure is from a woman who complained she had been experiencing chest pain for several days. What is the rhythm? Is there complete AV block?

Zavegepant Nasal Spray (Zavzpret)

Zavegepant can be prescribed to treat migraine, with or without aura, in adults.

Multivitamin-Mineral Supplementation vs. Cocoa Extract for Cognition

Researchers followed participants for three years and determined daily cocoa supplement use was not associated with cognitive enhancement in older adults, whereas a multivitamin supplement was associated with significant cognitive benefits.

Insulin Resistance at the Blood-Brain Barrier in Alzheimer’s Disease

Alterations in cerebrovascular insulin receptor isoform levels were associated with Alzheimer’s disease pathology and caused deficits in insulin signaling at the level of the blood-brain barrier.

OB/GYN Clinical Alert Celebrates 40 Years

Does Topiramate Decrease the Efficacy of Oral Contraceptives?

In this retrospective cohort study, women taking low-dose topiramate (< 200 mg per day) and oral contraception did not have more contraceptive failures compared to women taking other headache remedies (propanolol, metoprolol, amitriptyline, venlafaxine, or verapamil), with an adjusted rate difference of 0.00 (95% confidence interval, -0.3, 0.3).

CIN2 Is More Likely to Progress if HPV 16 Is Present

This study examined rates of cervical intraepithelial neoplasia grade 2 (CIN2) regression and progression among women ages 25-30 years and found that regression rates varied by human papillomavirus (HPV) genotype: 51% regression and 47% progression in HPV 16 infections compared to 83% regression and 16% progression for infections with other HPV types.

Diagnosis of Obstructive Sleep Apnea During Pregnancy

Obstructive sleep apnea is associated with several adverse maternal and fetal outcomes.