Clinical
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Does Your Patient Have a Central Venous Catheter?
Central venous catheters (CVCs) are essential to providing optimal care to many hospitalized patients.
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Neuroimaging Differences in Dyslexics: Chicken or Egg?
Neuroanatomical differences in primary sensory cortices may distinguish dyslexic individuals from non-dyslexic individuals, providing a potential biomarker for identifying adults who may be predisposed to developing atypical neurodegenerative disease. -
Take Me Out of the Ball Game: Acute Management and Long-term Consequences of Concussion in Childhood
The developing brain of a child may be particularly susceptible to injury from mild traumatic brain injury, such as a concussion. Recommending a longer period of strict rest after a concussion does not provide additional benefit when compared to consensus guidelines for care after a concussion in children and adolescents. However, in retired former NFL players, exposure to tackle football prior to age 12 is associated with executive dysfunction, memory impairment, and lower estimated verbal IQ later in life. -
Endometrial Protection: Which Progestogen Is Best?
After a lost decade, increasing numbers of women and providers are recognizing the benefits of postmenopausal hormonal therapy. For women with an intact uterus, endometrial protection is required when systemic estrogen therapy is used. Since activity at the glucocorticoid and androgen receptor may lead to adverse health effects in some women, use of pure progesterone receptor agonists may offer advantages. However, the use of natural progesterone is problematic due to low potency and poor bioavailability with oral dosing. Local therapy with the levonorgestrel intrauterine device (off-label) may be an excellent choice for many women. -
Delayed Cord Clamping
Although a recent study has failed to show major benefit from delayed umbilical cord clamping, others have suggested neonates having delayed cord clamping have less need for transfusion, higher hematocrits, less neonatal morbidity, and diminished risk of intraventricular hemorrhage. -
Intercourse at the Time of Implantation Confers Lower Chance of Conception
Couples attempting natural conception were found to have a lower chance of success per cycle when intercourse took place at or around the time of implantation. -
Weight Gain with Contraception
In this prospective cohort study, perceived weight gain was found to be an adequate predictor of actual weight gain. Depot medroxyprogesterone acetate and the contraceptive implant were associated with more weight gain than the copper IUD. -
Reassuring Safety Data about Incretins and CHF
The class of medications used to treat diabetes (and obesity) known as “the incretins” includes several DPP4 inhibitors and GLP1 agonists. These agents have achieved a favorable status in prescribing algorithms because of the combination of their low risk of hypoglycemia, impact upon weight (neutral for DPP4, weight loss for GLP1), and effects on postprandial glucose attributed to glucagon blunting.
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Every-other-day Tadalafil for Lower Urinary Tract Symptoms and Erectile Dysfunction
Although the incidence of erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) both increase with age, there is an as-yet ill-explained independent association of LUTS with ED. That is, within each age decile, more severe LUTS is associated with more severe ED.
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Modifying the Home Environment to Prevent Falls
Falls in the home setting are a commonplace source of serious injury. In the recent past, most studies to address falls have addressed children, disabled persons, or the elderly. There is little information on more general populations, or whether a standardized set of environmental modifications — not designed to address any specific disability — would reduce falls and their consequences.